Canadian Sciences Speakers Network

Réseau Canadien de Panélistes Scientifiques

Lisa Porter

Windsor, Ontario

Position: Distinguished Professor

Organization: University of Windsor

Dr. Lisa Porter is passionate about the value that research excellence brings to the health and care of the community that we serve. She leads a team of scientists and students to find new and better ways to rapidly detect and treat cancer. She has a deep appreciation for the importance of multi-disciplinary, collaborative research conducted with patients and the community to ensure rapid and effective translation of results and knowledge which fosters innovation & impact in the healthcare system.

Areas of Expertise:

+ Cancer

+ Research communications

+ Health

Language(s):

+ English

About Me

English proficiency: Read, Write, Speak

Willing to Mentor: Yes

Title: Dr.

Pronouns: She/Her/Hers

Gender: Female

Recent Publications

Title	Year
Atypical cell cycle regulation over neural stem cell expansion	2026
Patient perspective of Hesitancies and strategies to increase cancer clinical trial participation	2026
Clinical Significance of Tumor Grade in Triple-Negative Breast Cancer: A Retrospective Cohort Analysis	2025
Modeling Glioma Stem Cell-Mediated Tumorigenesis Using Zebrafish Patient-Derived Xenograft Systems	2025
Profiling Glioma Stem Cell Dynamics via 3D-Based Cell Cycle Reporter Assays	2025
Long-Term Survival in Human Epidermal Growth Factor Receptor 2-Positive Bone-Only Metastatic Breast Cancer: Trastuzumab, Denosumab, and Potential Synergistic Effects	2024
Regulation of biological processes by ubiquitin ligases: a focus on the Pagano Lab’s contribution	2024
Atypical cell cycle regulation promotes mammary stem cell expansion during mammary development and tumourigenesis	2024
High‐impact practices in cancer education and research: Undergraduate students’ perceptions of skills and career development	2024
Abstract PO3-03-09: Clinical Significance of Grade in Triple Negative Breast Cancer	2024
Su1134 TARGETED GENE SEQUENCING OF SPORADIC YOUNG-ONSET COLON CANCER SAMPLES USING TRUSIGHT ONCOLOGY 500 FROM ILLUMINA IDENTIFIES RECURRENT MUTATIONS IN DDR2 ONCOGENE.	2024
Evaluating and optimizing Acid-pH and Direct Lysis RNA extraction for SARS-CoV-2 RNA detection in whole saliva	2024
Presentation and Outcome of Patients with Multiple Myeloma (MM), Single Centre Experience from Windsor Essex Regional Cancer Centre	2024
Comparative genomic analysis to identify a signature of sporadic colorectal cancer development in young adults.	2024
EXPLORING THE INTERPLAY BETWEEN BRAIN TUMOUR INITIATING CELLS AND THE TUMOUR MICROENVIRONMENT: POTENTIAL TARGETING STRATEGIES FOR GLIOBLASTOMA	2023
Actionable wastewater surveillance: application to a university residence hall during the transition between Delta and Omicron resurgences of COVID-19	2023
Abstract P4-07-60: Identification of Optimal Carboplatin Containing Regimen for Triple Negative Breast Cancer	2023
Comprehensive gene sequencing to identify progression predictors to muscle-invasive bladder cancer.	2023
Tuberin levels during cellular differentiation in brain development	2022
Frequently used antiemetic agent dexamethasone enhances the metastatic behaviour of select breast cancer cells	2022
Stabilization of c-Myc by the atypical cell cycle regulator, Spy1, decreases efficacy of breast cancer treatments	2022
Dissecting the roles of the Tuberin protein in the subcellular localization of the G2/M Cyclin, Cyclin B1	2022
Impairing proliferation of glioblastoma multiforme with CD44+ selective conjugated polymer nanoparticles	2022
Fitted filtration efficiency and breathability of 2-ply cotton masks: Identification of cotton consumer categories acceptable for home-made cloth mask construction	2022
A prospective phase II clinical trial identifying the optimal regimen for carboplatin plus standard backbone of anthracycline and taxane-based chemotherapy in triple negative breast cancer	2022

Filter Your Publications

Select Publications to Filter (122)

Atypical cell cycle regulation over neural stem cell expansion

Patient perspective of Hesitancies and strategies to increase cancer clinical trial participation

Clinical Significance of Tumor Grade in Triple-Negative Breast Cancer: A Retrospective Cohort Analysis

Navigating healthcare realities: exploring access and engagement for transgender and non-binary individuals in England

Modeling Glioma Stem Cell-Mediated Tumorigenesis Using Zebrafish Patient-Derived Xenograft Systems

Profiling Glioma Stem Cell Dynamics via 3D-Based Cell Cycle Reporter Assays

Long-Term Survival in Human Epidermal Growth Factor Receptor 2-Positive Bone-Only Metastatic Breast Cancer: Trastuzumab, Denosumab, and Potential Synergistic Effects

Regulation of biological processes by ubiquitin ligases: a focus on the Pagano Lab’s contribution

Atypical cell cycle regulation promotes mammary stem cell expansion during mammary development and tumourigenesis

High‐impact practices in cancer education and research: Undergraduate students’ perceptions of skills and career development

Abstract PO3-03-09: Clinical Significance of Grade in Triple Negative Breast Cancer

Su1134 TARGETED GENE SEQUENCING OF SPORADIC YOUNG-ONSET COLON CANCER SAMPLES USING TRUSIGHT ONCOLOGY 500 FROM ILLUMINA IDENTIFIES RECURRENT MUTATIONS IN DDR2 ONCOGENE.

Evaluating and optimizing Acid-pH and Direct Lysis RNA extraction for SARS-CoV-2 RNA detection in whole saliva

Presentation and Outcome of Patients with Multiple Myeloma (MM), Single Centre Experience from Windsor Essex Regional Cancer Centre

Comparative genomic analysis to identify a signature of sporadic colorectal cancer development in young adults.

EXPLORING THE INTERPLAY BETWEEN BRAIN TUMOUR INITIATING CELLS AND THE TUMOUR MICROENVIRONMENT: POTENTIAL TARGETING STRATEGIES FOR GLIOBLASTOMA

Actionable wastewater surveillance: application to a university residence hall during the transition between Delta and Omicron resurgences of COVID-19

Abstract P4-07-60: Identification of Optimal Carboplatin Containing Regimen for Triple Negative Breast Cancer

Comprehensive gene sequencing to identify progression predictors to muscle-invasive bladder cancer.

Tuberin levels during cellular differentiation in brain development

Frequently used antiemetic agent dexamethasone enhances the metastatic behaviour of select breast cancer cells

Stabilization of c-Myc by the atypical cell cycle regulator, Spy1, decreases efficacy of breast cancer treatments

Dissecting the roles of the Tuberin protein in the subcellular localization of the G2/M Cyclin, Cyclin B1

Impairing proliferation of glioblastoma multiforme with CD44+ selective conjugated polymer nanoparticles

Fitted filtration efficiency and breathability of 2-ply cotton masks: Identification of cotton consumer categories acceptable for home-made cloth mask construction

A prospective phase II clinical trial identifying the optimal regimen for carboplatin plus standard backbone of anthracycline and taxane-based chemotherapy in triple negative breast cancer

Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells

A revised synthesis of 6-alkoxy-2-aminopurines with late-stage convergence allowing for increased molecular complexity

Barriers to translational research in Windsor Ontario: a survey of clinical care providers and health researchers

A Retrospective Single Center Study Investigating the Clinical Significance of Grade in Triple Negative Breast Cancer

Averting an Outbreak of SARS-CoV-2 in a University Residence Hall through Wastewater Surveillance

The Cyclin-Like Protein SPY1 Overrides Reprogramming Induced Senescence Through EZH2 Mediated H3K27me3

PREVENT: A Randomized, Placebo-controlled Crossover Trial of Avexitide for Treatment of Postbariatric Hypoglycemia

The Role of Human Endothelial Cells in the Brain Tumour Organoid (BTO) Platform as a Unique Tool in Discovery of Novel Treatment Approaches in Glioblastoma

Health Care Workers and Patients as Trojan Horses: a COVID19 ward outbreak

P-370 Comprehensive targeted genomic profiling and comparative genomic analysis to identify molecular mechanisms driving cancer progression in young-onset sporadic colorectal cancer

Comprehensive targeted gene profiling to determine the genomic signature likely to drive progression of high-grade nonmuscle invasive bladder cancer to muscle invasive bladder cancer.

Treatment Timing of Triple-Negative Breast Cancer

Conjugated Polymer Nanoparticles: A Novel Strategy to Combat Glioblastoma Multiforme

The role of cooperating mutations in Spy1 mediated expansion of Brain Tumour Initiating Cells

The Role of Spy1 During Mammary Involution

Differential Expression of Glucose Transporters and Hexokinases in Prostate Cancer with a Neuroendocrine Gene Signature: A Mechanistic Perspective for 18F-FDG Imaging of PSMA-Suppressed Tumors

The atypical cyclin-like protein Spy1 overrides p53-mediated tumour suppression and promotes susceptibility to breast tumourigenesis

Cyclin-like proteins tip regenerative balance in the liver to favour cancer formation

A Network-based Machine Learning Approach for Identifying Biomarkers of Breast Cancer Survivability

Neuro‐ and hepatic toxicological profile of (S)‐2,4‐diaminobutanoic acid in embryonic, adolescent and adult zebrafish

1085-P: Dance 501 Inhaled Human Insulin (INH): Linear Dose Response, Earlier Onset of Action, and Higher Early Effect than s.c. Insulin Lispro (LIS)

OR20-5 28-Day Dosing with Avexitide Improves Hyperinsulinemic Hypoglycemia in Patients with Severe, Refractory Post-Bariatric Hypoglycemia: The PREVENT Study

The Tuberin and Cyclin B1 complex functions as a novel G2/M sensor of serum conditions and Akt signaling

Transcriptomics Signature from Next-Generation Sequencing Data Reveals New Transcriptomic Biomarkers Related to Prostate Cancer

Cell Cycle Dynamics in Glioma Cancer Stem Cells

Neuroendocrine differentiation of prostate cancer leads to PSMA suppression

The Localization of Spy1 Protein in the Neurogenic Niche of the Subventricular Zone: Implication in Neural Stem Cell Pool Regulation.

The Role of Tuberin and Cyclin B1 as a DNA Damage Response during the G2/M Transition

Role of Mechanical and structural properties of GBM microenvironment in tumour aggressiveness and therapy resistance

The Role of Spy1 in the Development of Hepatocellular Carcinoma

The Novel Role of GABAB and CXCR4 in Medulloblastoma

The Role of Spy1 in Glioblastoma Multiforme Initiation and Progression

Novel Approach in Resolving the Mechanism Behind Brain Tumour Heterogeneity and Therapy Response

Role of Spy1 in Mammary Development

Structural basis of divergent cyclin‐dependent kinase activation by Spy1/ RINGO proteins

An Integrative Approach for Identifying Network Biomarkers of Breast Cancer Subtypes Using Genomic, Interactomic, and Transcriptomic Data

The cyclin-like protein, SPY1, regulates the ERα and ERK1/2 pathways promoting tamoxifen resistance

Activated thrombin-activatable fibrinolysis inhibitor attenuates the angiogenic potential of endothelial cells: potential relevance to the breast tumour microenvironment

Novel Biomarkers for Prostate Cancer Progression

Cell Size regulation by a New Cell Cycle checkpoint: Characterization of clinically relevant Tuberin mutants

Targeting the Novel Cell Cycle Regulator, Spy1, for Treatment of Medulloblastoma

The dual inhibition of RNA Pol I transcription and PIM kinase as a new therapeutic approach to treat advanced prostate cancer

Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates breast cancer cell metastatic behaviors through inhibition of plasminogen activation and extracellular proteolysis

A novel model used to detect differential splice junctions as biomarkers in prostate cancer from RNA-Seq data

Direct interactions with both p27 and Cdk2 regulate Spy1-mediated proliferationin vivoandin vitro

The Efficacy of Targeting Cell Cycle Regulators in the Treatment of Medulloblastoma

Exploring a Link Between Spy1 and Hepatocellular Carcinoma Progression

Sodium salicylate reduces the level of GABAB receptors in the rat’s inferior colliculus

Paclitaxel-induced transcriptional regulation of Fas signaling pathway is antagonized by dexamethasone

Identifying differentially expressed transcripts associated with prostate cancer progression using RNA-Seq and machine learning techniques

A novel approach for finding informative genes in ten subtypes of breast cancer

Abstract P1-07-32: Activated thrombin activatable fibrinolysis inhibitor is a novel anti-metastatic factor in breast cancer

Single nucleotide polymorphisms of the renin angiotensin system linked to high prevalence of essential hypertension in the Taita tribe of Kasigau, Kenya

Visualizing the Tuberin-CyclinB1 Interaction at the G2/ M Transition

Effect of Media on Biofilter Performance Following Ozonation of Secondary Treated Municipal Wastewater Effluent: Sand vs. GAC

Derivation of a novel G2 reporter system

Breast cancer subtype identification using machine learning techniques

The atypical cell cycle regulator Spy1 suppresses differentiation of the neuroblastoma stem cell population

The Cyclin-like Protein Spy1 Regulates Growth and Division Characteristics of the CD133+ Population in Human Glioma

Exenatide once weekly versus liraglutide once daily in patients with type 2 diabetes (DURATION-6): a randomised, open-label study

Exenatide at therapeutic and supratherapeutic concentrations does not prolong the QTc interval in healthy subjects

The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer

Differences in metabolic effects of twice daily versus multiple daily insulin injections in children with type 1 diabetes

pH Effects on the Bio-Permeability of Polymers Used in Prophylactics

The tumor suppressor tuberin regulates mitotic onset through the cellular localization of cyclin B1

The level and distribution of the GABABR2 receptor subunit in the rat’s central auditory system

DURATION-5: Exenatide Once Weekly Resulted in Greater Improvements in Glycemic Control Compared with Exenatide Twice Daily in Patients with Type 2 Diabetes

DURATION-2: Exenatide einmal wöchentlich erreicht nach 26 Behandlungswochen bessere Blutzuckerkontrolle und Gewichtsreduktion als Sitagliptin oder Pioglitazon

Exenatide einmal wöchentlich: Anhaltende Blutzuckerkontrolle und Gewichtsreduktion über einen Behandlungszeitraum von 2 Jahren

Abnormalities in Pancreatic Enzyme Levels in Otherwise Asymptomatic Subjects with Type 2 Diabetes

Randomized Comparison of Pramlintide or Mealtime Insulin Added to Basal Insulin Treatment for Patients With Type 2 Diabetes

Pramlintide Lowered Glucose Excursions and Was Well-Tolerated in Adolescents with Type 1 Diabetes: Results from a Randomized, Single-Blind, Placebo-Controlled, Crossover Study

Exenatide einmal wöchentlich: Anhaltende Blutzuckerkontrolle und Gewichtsreduktion über 52 Wochen

The Cyclin-dependent Kinase Activator, Spy1A, Is Targeted for Degradation by the Ubiquitin Ligase NEDD4

Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study

The Spy1/RINGO Family Represents a Novel Mechanism Regulating Mammary Growth and Tumorigenesis

Spy1 Enhances Phosphorylation and Degradation of the Cell Cycle Inhibitor p27

GASTROINTESTINAL SYMPTOMS IN CHILDREN WITH TYPE I DIABETES SCREENED FOR COELIAC DISEASE

1124-192 Rosiglitazone reduces novel biomarkers of cardiovascular disease in subjects with type 2 diabetes mellitus already on statin therapy

Spy1 Interacts with p27Kip1 to Allow G1/S Progression

Human Spy1 promotes survival of mammalian cells following DNA damage.

Nuclear localization of cyclin B1 regulates DNA damage–induced apoptosis

Spy1 interacts with p27Kip1 to allow G1/S progression

Cyclin B1 and CDK1: nuclear localization and upstream regulators.

USE OF MUTAGENESIS TO STUDY THE TRANSLOCATION OF ANNEXIN 1 ACROSS THE CELL MEMBRANE

Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

Human Speedy

Prevalence of self-reported arm morbidity following treatment for breast cancer in the Australian Breast Cancer Family Study

α-, β-, and γ-Tubulin Polymerization in Response to DNA Damage

KIR6.1 K+ channel subunits are expressed in mouse ventricular myocytes and associate with the actin cytoskeleton

Abundance of cyclin B1 regulates γ-radiation–induced apoptosis

Calcium modulation of the renin-aldosterone axis

Hyperglycemia and Angiotensin-Mediated Control of the Renal Circulation in Healthy Humans

BRCA1 mutations and other sequence variants in a population-based sample of Australian women with breast cancer

Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group.

Improved survival of hemorrhagic shock with oxygen and hypothermia in rats

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