Glen Pyle
Hamilton, Ontario
Position: Professor
Organization: University of Guelph, IMPART Network at Dalhousie Medicine, and Women’s Health Research Institute at BC Women’s HospitalBC Women’s
Glen Pyle is a Professor of Molecular Cardiology and a member of the IMPART Network at Dalhousie Medicine and the Women’s Health Research Institute at BC Women’s Hospital. His lab focuses on women’s cardiovascular health, including the impacts of menopause and intimate partner violence on heart attack deaths, and the development of therapies to reduce these risks. The team was the first to identify how the hearts of women are altered during the transition to menopause (“perimenopause”) and explain how these changes contribute to the higher risk of cardiovascular disease death in postmenopausal women. In 2024, the team received funding from the National Women’s Health Research Initiative to investigate the relationship between intimate partner violence or “domestic abuse” and an increase in heart attack mortality in women. The Laboratory for Women’s Heart Health (www.womensheartlab.com) has been supported with grants from the Heart and Stroke Foundation of Canada, Canadian Institutes of Health Research, National Sciences and Engineering Research Council of Canada, and the U.S. National Institutes of Health.
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My Work
What I do:
Our lab is investigating how sex differences in the heart impact heart disease risk. Specifically we are interested in how menopause and intimate partner violence impact women’s risk of dying from heart attacks. We use animals models to determine the mechanisms of risk at the molecular level, and develop interventions that may lower these risks.
Ask me about:
Women’s heart health; menopause; intimate partner violence and cardiovascular disease; sex differences in cardiovascular disease
Why me:
We are among the first to identify how the heart changes during the perimenopausal transition at the molecular level. We have identified early changes in animal models of menopause that may contribute to the increased risk of cardiovascular disease mortality seen in postmenopausal women. We are actively engaged in communicating our work and the current state of women’s cardiovascular health to both our professional peers, and the public at large. We regularly speak at public gatherings and have given numerous media interviews.
About Me
Sector: Academia (Post Secondary)
English proficiency: Read, Write, Speak
Title: Dr.
Pronouns: He/Him/His
Gender: Male